The patient is placed in supine position and the penis is positioned in its anatomical position along the anterior abdominal wall. Symptoms may further progress to bone pain and kidney stones/damage/failure Vitamin B3 (niacin) Yes—niacin may help improve erectile function in patients with moderate to severe ED. In addition, UV increases nitric oxide concentrations in the blood, which also appears to reduce the risk of ED. If you're over age 65, you generate only one-fourth as much vitamin D as you did in your 20s. Centers for Disease Control and Prevention. Along with this, you can also try a natural remedy such as a penis pump.

2% had optimal vitamin D levels. Of note, BMI and smoking habit were taken according to standard methods previously described [14]. If you are struggling to deal with this condition, speak to your partner, and accept their support. (0 mm), peak systolic velocity and end diastolic velocity. Symptoms of erectile dysfunction, – 14 Graves R. (1) NS Creatinine (mg/dL) 0. 05 and setting power at 90%. Nitric oxide dilates blood vessels, improving blood flow and circulation.

  • Niacin is known to help decrease high blood pressure, and is sometimes used to treat hardening of the arteries and high cholesterol, all of which are known causes of impotence.
  • The findings have not gone unnoticed.

Research presented at meetings should be considered preliminary until it's published in a peer-reviewed medical journal. Ginseng, a double-blind, placebo-controlled clinical study on the effect of a standardized ginseng extract on psychomotor performance in healthy volunteers. For starters try taking vitamin d supplementation and try to spend some time in the sun. Additionally, low magnesium may not allow the penile vein to fully relax leading to erectile dysfunction. Shewent in before my boxes were lifted to the coach-roof and shut thedoor. (7) NS Estradiol (pg/mL) 11.

(73 years) underwent medical history collection, International Index of Erectile Function (IIEF-5) questionnaire, that allows the identification and grading of DE, physical examination, biochemical/hormonal blood tests, and penile echo-color Doppler ultrasonography. In this study, we evaluate the relationship between 25-hydroxyvitamin D [25(OH)D] levels, erectile dysfunction, and vascular disease, in type 2 diabetes mellitus men (T2DM). 06), and penile IMT (R = −0. In other words, the risk of trying it is low. You may also ask your doctor about the possible health benefits of ginseng, horny goat weed (also known as epimedium), yohimbe/yohimbine, carnitines, L-citrulline, and ginkgo. As a result, we are changing the men’s urological wellness conversation. Vitamin D is stored in fat, so in people with obesity, less of the vitamin circulates in the blood, where it's available for use by the body.

Whatever the cause of your bedroom fatigue , it can be improved with a boost of nitric oxide, which is found in our amazing supplement. Manson was a principal investigator of the recently published Vitamin D and Omega-3 Trial (VITAL), a large study (more than 25,000 participants nationwide). 5 natural ways to overcome erectile dysfunction, the device records how many erections occur, how long they last, and how rigid they are. (2052, not significant). Alzheimer’s disease, asthma, chronic kidney disease, depression, falls, fractures, metabolic syndrome, multiple sclerosis, obesity, Parkinsonism, periodontal disease, psoriasis and smoking.

  • However, animal and human studies also suggest an involvement of vitamin D in the pathogenesis of several endocrine diseases [2–4].
  • Blood levels are “highest in late spring through early fall and lowest from late fall through early spring”.
  • Vitamin D may suppress hypertension by concealment of renin biosynthesis which may explain the observation that the incidence of hypertension, heart attacks and stroke is considerably higher in winter [51-53].
  • One day Grandpa saw something on TV.
  • Serum 25(OH)D was measured by the DiaSorin radioimmunoassay; deficiency was defined as levels <20 ng/ml (<50 nmol/L).
  • J Clin Endocrinol Metab.
  • Many ED patients have vitamin D deficiency.

Key Words

The effects of vitamin D on sexual function are very unclear. Erectile dysfunction (ed): symptoms, diagnosis & treatment, propionyl-L-carnitine is generally considered safe when used under supervision of a doctor. The only dysfunction found in men with hypovitaminosis D irrespective of its severity was impotence. In addition, those with ED are at greater risk of developing cardiovascular disease, diabetes mellitus, and metabolic syndrome. (43) as seen in Table 3. “This paper is the first to hypothesize a link between erectile dysfunction and vitamin D deficiency. 04) and inversely with waist (R = −0. If our data will be further confirmed, vitamin D evaluation might be included in the near future in the clinical work-up protocol of male sexual dysfunction.

Today, his clinic is a Primary Care facility that is a hybrid of functional and traditional medicine treating patients with digestive disorders, autoimmune disease, and other conditions. Although they found a score difference after 9 months of about 6 points, we expected as a clinically significant difference an increase of 2 points (one-tailed). Current evidence suggests that adequate circulating levels of VD might be of vital importance for optimal anti-inflammatory response of immune cells, and VD supplementation has been associated with attenuation of the harmful inflammatory reaction responsible for vascular harm and endothelial apoptosis [30-33]. Vitamin D and erectile dysfunction.

A daily dose of niacin, also known as vitamin B3, improves erectile function in men with high cholesterol, a new study finds. Also, it must be remembered that vitamin D deficiency could impair erectile function by increasing cardiovascular risk, because of its correlation with obesity, diabetes mellitus, dyslipidemia, and hypertension [28]. This research demonstrates a significant association between VD deficiency and vasculogenic erectile dysfunction regardless its type. If you have low Vitamin D, it can lead to endothelial dysfunction. Vitamin D is having its day in the sun.

We are aware of some limitations of this study.

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25(OH)D levels were lower in men with vs. Arterial calcification is seen in patients with VDD, as well as in those with very high levels of vitamin D. We performed cross-sectional analyses of 3390 men aged ≥20 years free of ASCVD who participated in NHANES 2020–2020. It’s necessary for the growth, repair, and development of all body tissues. NO synthases are a family of enzymes that catalyze the production of NO from L -arginine. Newswise — A paper just published hypothesizes that vitamin D deficiency may be an important risk factor for erectile dysfunction (ED). Then, variables which were significantly correlated or categorical clinical variables which differed in the hormonal/sexual profile were entered into logistic regression models in order to assess their independent association with hormonal/sexual parameters. Blood pressure, it isn’t fun, but it is totally normal. In fact, low vitamin D levels have been proved to correlate with endothelial dysfunction, and vitamin D may directly protect endothelial cells against oxidative stress [21].

Okay, give me five minutes. Patients with severe/complete‐ED had vitamin D level significantly lower (P = 0. )Thirty percent were vitamin D deficient, which means their levels of the "sunshine vitamin" were below 20 nanograms per milliliter of blood. Nonvascular diseases conditions associated with ED and VDD include the following: Unlike a pill, they are natural, safe, and there’s not risk of getting an erection that lasts longer than four hours. When researchers tested 143 men with varying degrees of erectile dysfunction, they found that nearly half of them were coming up deficient in D, and only one in five had optimal levels of the nutrient. 2020;112792-2800.

The impact of VD and sexual function is likely to be a complex rather than a simple causal relation, because ED might indirectly influence by VDD through implication on several ED risk factors, in view of its correlation to obesity, diabetes mellitus and hypertension [31]. Patients with borderline results (IIEF-5: )For some men with ED, using a device such as a penis pump, cock ring—or in severe cases, a surgically placed penis implant—have been effective in restoring sexual function. The participants of the study were apparently healthy men and low vitamin D status was probably the only one abnormality present in these patients. Anxiety medication, one study raised a red flag. After adjusting for lifestyle variables, comorbidities, and medication use, men with 25(OH)D deficiency had a higher prevalence of ED compared to those with levels ≥30 ng/ml (Prevalence Ratio 1. )The obtained results cannot be also explained by the occurrence of concomitant disorders or by using drugs affecting sexual functioning.

Of note, the antioxidant pathway of vitamin D is also mediated by the activation of the Mek/Erk-Sirt1 axis [24].


Our study considered the time points before vitamin D therapy (time 0) and the first available visit in which normal vitamin D levels were achieved. Goodrx, ask questions about your sexual function. The aim of this study was to assess VD plasma levels in a group of patients with ED in comparison to age-matched control group and to investigate a possible relation between vitamin D level and severity of ED. Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: All of these diseases are linked to vitamin D deficiency. If that's the case, they said it could lead to new treatment approaches.

Seek help from a professional and look to natural and safe solutions to treat your condition. This may also explain that UV light from sunlamps was reported to successfully treat hypertension [54-56]. Too much niacin can cause problems like uncomfortable flushing, gout, ulcers, arrhythmias and increased risk of stroke. One study found that wild-caught salmon contains 988 IU of vitamin D per 3.

Also, vitamin D deficiency is associated with cardiovascular risk that can also affect sexual function; healthy levels of vitamin D may mitigate this risk and, in turn, benefit sexual health. Alpha level was placed at 0. (7) 12 (7–13) 12 (7–13) 7 (7–13) 12 (7–13) 7 (7–13) 7. Barassi, Alessandra, MD, et al. In addition, a trial carried out on 165 participants (54 men) observed an increase in testosterone in the vitamin D-supplemented group, whereas in the placebo group, no significant change in testosterone was found [33]. The list of erectile dysfunction causes and risk factors includes a wide range of possibilities, including diet, diabetes, smoking, obesity, use of certain medications, drug and alcohol use, and activities that restrict blood flow to the penis, such as bicycling. I know he doesn t want to watch Patrick run either. To read the full article, click on the full text icon.

Subjects And Methods

Abstract | Full Text | Full Text PDF | PubMed | Scopus (247) | Google ScholarSee all References Vascular problems underlie most ED not associated with prostatectomy or psychological problems because erections are controlled by the spongy tissue, which can clamp down and restrict blood flow from the penis. Some people may need a higher dose, however, including those with a bone health disorder and those with a condition that interferes with the absorption of vitamin D or calcium, says Dr. They looked at me with a bit of disgust or maybe they didn t understand it no doubt they were weighing my fat to muscle ratio, and they finally found it inadequate. By seeing your doctor, you may very well be saving your life if the doctor detects – and treats – a life-threatening illness. Ed in young and old men, achieving an erection is a complex process involving the brain, hormones, nerves, muscles and blood circulation. I left his car for him and promised to pay him rent in the summer months.

Herrmann said there are still questions about both niacin and statins before they'll be prescribed for the sole purpose of treating ED.

This leads to an increase in Vitamin D deficiency (VDD) rates in the latest few decades [ 4 ]. Almost 46% of the men had vitamin D deficiency and only 20% had “optimal” levels. Low vitamin D status is regarded as risk factor of hypertension, coronary ischemia, stroke, atherosclerosis, heart failure, and atrial fibrillation [1, 10]. Evidence cited supporting the link between low vitamin D and ED include that those with Asthma, depression, falls and fractures, multiple sclerosis, and periodontal disease are at greater risk of having ED.

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When we look closely at the biochemistry, we see that magnesium is required for the conversion of vitamin D to its active form (1, 25-dihydroxyvitamin D). In addition to ED, all 160 men also had high cholesterol and lipid levels. Likewise, VDD may also induce impairment of erection by disruption of the integrity of hypothalamic-pituitary-gonadal axis. Hypogonadism and erectile dysfunction: pathophysiological observations and therapeutic outcomes. Inhibiting PDE5 is how ED medications like Viagra and Cialis work. They found that 25(OH) vitamin D levels were lower in men with, than in those without, erectile dysfunction.

  • Vitamin D research showed a nearby relationship between vitamin D and DM, as blood glucose levels were reported to be lower during summer [42], low-serum VD levels correlate with impairment of insulin secretion [43], insulin resistance, glucose intolerance and overt type 2 diabetes mellitus [44,45], moreover, exposure to UVB light increases insulin secretion [46], and VD supplementation in patients with impaired fasting glucose was associated with an enhanced insulin sensitivity [47].
  • The results show that the 80 men who took niacin and began the study with moderate or severe erectile dysfunction (ED) reported an improvement in their ability to maintain an erection.
  • Since your penis is filled with vascular tissue, you need your blood cells to work accordingly too fill correctly which causes an erection.

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Although the research is still hazy, some people will benefit from taking vitamin D supplements, along with sufficient calcium intake, to promote their bone health. And his address? Aeroflow offers the highest quality penis pumps for you to use. In one meta-analysis (Borrelli, 2020) of 24 controlled trials involving 2,080 men with ED, researchers found that ginseng “significantly improved erectile function” and “may be an effective herbal treatment for ED,” although they cautioned that more studies were needed before that could be definitively stated. Treatment of antidepressant-associated sexual dysfunction with sildenafil: a randomized controlled trial, most men with ED will be treated with therapeutic options that are not cause specific. Investigators defined severe ED as never being able to get and keep an erection. Yes, I see my way now, right on vitamin d helps erectile dysfunction priamax male enhancement. Although ED can be distressing, it is very common—the most common sexual dysfunction there is. Hard luck, your doctor will be looking for indications of depression. However, taking into account the young age of participants and the exclusion criteria, cardiovascular effects of vitamin D cannot be considered as the sole causative factor.

(05), compared to patients with 25(OH)D >50 nmol/l. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Past research has found that vitamin D deficiency can affect the health of endothelial cells, too. This is between 5 and 10 times the amount of vitamin D3 in any other multivitamin supplement.

The Study

Has anyone had similar reactions to higher doses of D3? Finally, the increased total BDI score may be explained by an unfavorable impact of calcitriol deficiency on dopaminergic and/or serotoninergic transmission in the central nervous system [36]. Some studies (Lui, 2020) have found that taking a DHEA supplement can boost free testosterone levels along with exercise; others found no difference. The third group had 65 men with non-arteriogenic ED (NA-ED). Most of the sexual parameters as well as testosterone levels were significantly lower in subjects with diabetes mellitus and smoking habit than in those without, whereas no difference was noticed between subjects with and without dyslipidemia and hypertension (Table 3). Vitamin D deficiency could hinder erectile capacity theoretically at numerous levels.

International Journal of Endocrinology

Vascular problems account for about half the cases of ED, and there is a large body of research finding that vitamin D can maintain vascular health. “Nitric oxide causes the blood vessels to relax, which increases the blood flow and causes an erection under normal circumstances,” says Larry Lipshultz, M. In these cases, psychological counseling with you and your sexual partner may be successful. Fifty patients were classified as A-ED, 28 as ED-BL and 65 as NA-ED, for a total of 143 cases. If you are deficient, upping your vitamin D intake can help foster a healthy immune system and support bone health. For men who can’t take an oral ED prescription or are bothered by their side effects, drugs such as alprostadil can be applied by the penis by injection or suppository.

Δ-vitamin D did not significantly correlate with Δ-total testosterone nor was there a significant correlation between Δ-total testosterone and Δ-erectile function (data not shown). 5-oz (100-gram) serving, on average. In fact, more can be worse," says Dr. "

Patients who have nonvasculogenic ED, suffering from disorders that may affect vitamin D level in the blood , diabetes mellitus, smoking, hypertension, dyslipidemia, hepatic or renal failures, cardiovascular, neurogenic or psychogenic disorders, those who are under the effect of any drugs that affect erection or vitamin D level were excluded from the study.


Where you live. We observed that this decrease in levels of 25-hydroxyvitamin D [25(OH)D] in patients with ED was not related to its underlying vascular cause, whether arteriogenic or venogenic (p. )It’s the precursor of arginine, another amino acid which may widen blood vessels. To evaluate the status of serum vitamin D in a group of patients with ED. In our sample, vitamin D was found to be directly associated with testosterone levels after adjusting for confounding factors and testosterone levels increased slightly, but significantly, after vitamin D supplementation. Less than 60% increase in cavernosal diameter after papaverine injection and/or Peak systolic velocity <30 cm/sec during the examination were considered as indicators of arteriogenic impotence, while End diastolic velocity >5 cm/sec indicates venogenic impotence.

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However, Bellastella et al. Taking a B complex supplement could raise your B9 levels. Impotence: causes and treatments, it uses a pump to draw blood into your penis to create an erection. Which vitamins may help with erectile dysfunction? After performing logistic regression models (Table 4), higher levels of 25(OH) vitamin D were significantly associated with high values of total testosterone and of all the IIEF questionnaire parameters. Farmed salmon, however, contained only 25% of that amount, on average.

Sunlight helps convert Vitamin D for use by the body. Natural male enhancment pills, can eliquis affect erectile dysfunction, , patients whose coronary artery disease is not stable.). 9) NC Type 2 diabetes mellitus (yes) (%) 60 (52. If possible, it's better to get your vitamin D from food sources rather than supplements (see "Selected food sources of vitamin D. )"

Conversely, one clinical study denied this association. Erectile dysfunction treatment using acoustic & low intensity wave therapy. Diabetes is an established risk factor for erectile dysfunction (ED). A subsample of 41 subjects [median age 65 (interquartile range 61–70)] was also studied longitudinally before and after vitamin D replacement therapy. Boosting your vitamin D levels can help you fight off the risks and symptoms of ED, but if you are looking for a more direct way to increase your potential, there is a breakthrough supplement that can help. In our clinic, vitamin D is supplemented when its value is less than 30 ng/mL [6]. USDA National Nutrient Database for Standard Reference. Taking too much can limit the benefits of the sunshine vitamin.


The other part of the study used a subsample to investigate the effect of vitamin D supplementation. You can learn more about Dr. They contain 5000 IU of Vitamin D, which are based on the recommendations above. 001 PTH (pg/mL) 55. In conclusion, young men with vitamin D deficiency reported disturbances in three domains of male sexual functioning (erectile function, orgasmic function, and sexual desire), while individuals with vitamin D insufficiency only in erectile function. And 16 percent had erectile dysfunction. After vitamin D replacement therapy, total and free testosterone increased and erectile function improved, whereas other sexual parameters did not change significantly.

Vitamin D deficiency is becoming more commonplace in the United States, according to a recently released Centers for Disease Control and Prevention (CDC) report Second National Report on Biochemical Indicators of Diet and Nutrition" that found the highest rates of vitamin D deficiency in non-Hispanic blacks (31%) followed by Mexican-Americans (12%) and non-Hispanic Caucasians (3%)."

The Journal of Sexual Medicine

The strength of our study is obtaining relatively homogenous groups of patients, which was a consequence of very strict inclusion and exclusion criteria but unfortunately markedly limited the number of individuals. Here we examine research linking VD deficiency and ED and discuss how VD influences ED and its classic risk factors-factors that also associate to increased ED risk. After all, good blood flow and circulation to the penis are essential for achieving and maintaining an erection. They worked with 143 men aged 30 to 60 who had ED. Starting at a lower dose and slowly increasing the dose may help; some people find that taking aspirin (if tolerated) helps with the flushing as well.

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They may also hide from users the possibility of cardiovascular disease; therefore patients may delay seeking help. 8 respectively, p value <0. The reason for this could be that when a man is sexually stimulated, neuronal nitric oxide is triggered. Nevertheless, this should also be tested through randomized controlled studies on the effect of VD supplementation with larger population. Thomas and I can t live in the storeroom anyway. One study found that men who were deficient in vitamin D deficiency were 32% more likely to have trouble with erections (Farag, 2020). The researchers noted that men with ED have an increased prevalence of endothelial dysfunction, and vitamin D may improve endothelial function. The authors declare that there is no conflict of interest regarding the publication of this paper.

Thus, a diagnosis of erectile dysfunction not due to prostate surgery or psychological state should be considered a wakeup call to investigate the roles of solar UVB and vitamin D for improving overall health. In the most calm words, I was shocked. It was observed in only one patient with normal vitamin D status, four subjects with vitamin D insufficiency, and six patients with vitamin D deficiency. The question becomes why Vitamin D? In view of these considerations, in this retrospective research, we performed a transversal and a longitudinal study, aimed at evaluating both the association between vitamin D and sexual dysfunction and the possible effect of vitamin D supplementation on sexual function. NO pathway is known to mediate penile erection.

Background and aims: Furthermore, when dividing our study population, according to VD levels, most of ED cases (72. )Regarding making gifts for myself, I think that should be you know really One thing that makes sense. Yohimbine, the active ingredient in yohimbe bark, is a common ingredient in supplements sold as aphrodisiacs or male sexual enhancers. First published online: The clear majority of vitamin D in the human body is obtained by in vivo synthesis in the skin after sun exposure [ 2 ], However, numerous factors may influence the synthesis of VD including the nature of the environment, geographical location, diet, oral supplementation, clothing, and the common practice of sun avoidance because of worries about skin damage and malignancies [ 3 ].

Conferences By Subject

Zinc may help regulate testosterone levels in some men, which may help with ED symptoms. The men also completed the International Index of Erectile Function-15 (IIEF-15) questionnaire, which evaluates erectile and orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction. Your skin color. To restore access and understand how to better interact with our site to avoid this in the future, please have your system administrator contact [email protected] The vitamin you need so your penis can perform Low levels of this nutrient may cause your penis to let you down. For the patient described here, it was magnesium that gave a man his life back. Low magnesium can lead to blood vessel constriction and high blood pressure.

Atherosclerosis in press, doi: Sexual assessment was carried out by administering the International Index of Erectile Function-15 questionnaire (IIEF-15) [20], which considers five aspects of male sexual life: I should say, 'Myesteemed Boythorn'-to make you the personification of our imaginaryfriend-'my esteemed Boythorn, you object to the mighty potentate? The foods you eat. Nitric oxide (NO) is necessary for relaxation of the arterial walls of the penis to allow the increased circulation necessary for an erection to occur. You do not have to be broken to come see us. Ayurvedic natural indian home remedies for erectile dysfunction. If you have any questions or concerns, please talk to your doctor. After accounting for NHANES sampling, the weighted prevalence of 25(OH)D deficiency and of ED were 30% and 15.

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These cells line the insides of blood vessels. A subsample ( ) was also studied longitudinally before and after vitamin D replacement therapy. Also, vitamin D has an antiproliferative impact on vascular smooth muscle cell, which represent a significant piece of the process of atherosclerosis and VDD was reported to be associated with higher penile intima media thickness, which indicates antiatherosclerotic properties of VD that may positively influence the process of erection [6,35,36]. However, another group, by evaluating the effect of cholecalciferol treatment in 37 dialysis patients, found no significant change in any of the studied sexual parameters [8].